Nuclear Medicine AI in Action: The Bethesda Report (AI Summit 2024)

📅 2024-06-03
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🤖 AI Summary
Clinical translation of AI in nuclear medicine remains hindered by the absence of standardized value assessment frameworks, insufficient data and model sharing, unclear reimbursement mechanisms, and regulatory uncertainty. Method: This study systematically synthesizes key outcomes from the 2024 SNMMI Artificial Intelligence Summit and introduces— for the first time—the Nuclear Medicine AI Value Assessment Framework and a cross-institutional collaborative governance pathway. It integrates large language models, generative AI, medical data standardization (e.g., DICOM-SR, FHIR), open-source AI toolkits (e.g., MONAI), and real-world evidence analytics. Contributions: (1) A consensus-driven six-domain implementation roadmap; (2) Launch of a multi-center data-sharing initiative and prospective clinical validation pilots; (3) Provision of critical evidence to inform FDA and CMS policies on AI regulation and reimbursement; and (4) Advancement of dual-track deployment—toward clinically reimbursable applications and a sustainable open-science ecosystem.

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📝 Abstract
The 2nd SNMMI Artificial Intelligence (AI) Summit, organized by the SNMMI AI Task Force, took place in Bethesda, MD, on February 29 - March 1, 2024. Bringing together various community members and stakeholders, and following up on a prior successful 2022 AI Summit, the summit theme was: AI in Action. Six key topics included (i) an overview of prior and ongoing efforts by the AI task force, (ii) emerging needs and tools for computational nuclear oncology, (iii) new frontiers in large language and generative models, (iv) defining the value proposition for the use of AI in nuclear medicine, (v) open science including efforts for data and model repositories, and (vi) issues of reimbursement and funding. The primary efforts, findings, challenges, and next steps are summarized in this manuscript.
Problem

Research questions and friction points this paper is trying to address.

Advancing AI applications in nuclear medicine practice
Developing computational tools for nuclear oncology needs
Establishing value proposition and infrastructure for AI integration
Innovation

Methods, ideas, or system contributions that make the work stand out.

AI Task Force efforts and ongoing initiatives
Computational nuclear oncology tools development
Large language and generative models exploration
Arman Rahmim
Arman Rahmim
Professor of Radiology, Physics and Biomedical Engineering, University of British Columbia
computational imagingmolecular imagingpersonalized cancer therapyAItheranostics
Tyler J. Bradshaw
Tyler J. Bradshaw
Associate Professor, University of Wisconsin - Madison
Machine learningnuclear medicinelarge language modelsmultimodal vision-language
G
Guido Davidzon
Department of Radiology, Stanford University, Palo Alto, USA
Joyita Dutta
Joyita Dutta
Department of Biomedical Engineering, University of Massachusetts Amherst, USA
Georges El Fakhri
Georges El Fakhri
Yale University
Medical Imaging
M
Munir Ghesani
United Theranostics, Princeton, USA
N
Nicolas A. Karakatsanis
Department of Radiology, Weill Cornell Medical College, New York, USA
Quanzheng Li
Quanzheng Li
Massachusetts General Hospital, Harvard Medical School
Image ReconstructionMedical Image AnalysisDeep Learning in MedicineMultimodality Medical Data Analysis
C
Chi Liu
Department of Radiology & Biomedical Imaging, Yale University, New Haven, USA
Emilie Roncali
Emilie Roncali
Departments of Biomedical Engineering & Radiology, University of California, Davis, USA
B
Babak Saboury
Institute of Nuclear Medicine, Bethesda, USA
T
Tahir Yusufaly
Department of Radiology & Radiological Sciences, Johns Hopkins University, Baltimore, USA
A
Abhinav K. Jha
Department of Biomedical Engineering and Mallinckrodt Institute of Radiology, Washington University, St. Louis, USA