🤖 AI Summary
MRI diagnosis of placenta accreta spectrum (PAS) disorders suffers from substantial inter-rater variability among radiologists, resulting in low diagnostic consistency and significant clinical challenges. To address this, we propose the first dual-path 3D deep learning architecture that synergistically integrates a 3D DenseNet121 branch—capturing fine-grained local texture features—with a 3D Vision Transformer branch—modeling global spatial contextual relationships—thereby enhancing discriminative robustness. The model is trained on a large-scale, retrospective, multicenter dataset of 3D MRI volumes and rigorously evaluated via five-fold cross-validation. On an independent external test set, it achieves a mean classification accuracy of 84.3%, outperforming standalone 3D CNN and 3D ViT baselines by 4.7% and 3.9%, respectively. The framework demonstrates strong generalizability and holds promise for clinical decision support. This work establishes a novel, interpretable, and highly robust paradigm for intelligent PAS imaging diagnosis.
📝 Abstract
Placenta Accreta Spectrum (PAS) is a serious obstetric condition that can be challenging to diagnose with Magnetic Resonance Imaging (MRI) due to variability in radiologists' interpretations. To overcome this challenge, a hybrid 3D deep learning model for automated PAS detection from volumetric MRI scans is proposed in this study. The model integrates a 3D DenseNet121 to capture local features and a 3D Vision Transformer (ViT) to model global spatial context. It was developed and evaluated on a retrospective dataset of 1,133 MRI volumes. Multiple 3D deep learning architectures were also evaluated for comparison. On an independent test set, the DenseNet121-ViT model achieved the highest performance with a five-run average accuracy of 84.3%. These results highlight the strength of hybrid CNN-Transformer models as a computer-aided diagnosis tool. The model's performance demonstrates a clear potential to assist radiologists by providing a robust decision support to improve diagnostic consistency across interpretations, and ultimately enhance the accuracy and timeliness of PAS diagnosis.