🤖 AI Summary
Simulation studies in causal inference often suffer from non-reproducible results and inefficient resource utilization due to arbitrary choices of the number of replications (J).
Method: We propose the Test-based Iterative Simulation Count Algorithm (TISCA), the first method to integrate Welch’s t-test with statistical power analysis for dynamically determining the minimal required number of replications. TISCA iteratively runs simulations until predefined constraints—significance level (α = 0.05), statistical power (80%), and minimum detectable effect (MDE)—are jointly satisfied.
Contribution/Results: TISCA ensures statistically justified, resource-sustainable, and verifiably comparable simulation designs. Empirical evaluation demonstrates that TISCA reduces the required number of replications from 1,000 to 500—cutting computational cost by 50%—while rigorously preserving inferential reliability. It establishes a new paradigm for estimator evaluation that is rigorous, efficient, and fully reproducible.
📝 Abstract
Evaluation of novel treatment effect estimators frequently relies on simulation studies lacking formal statistical comparisons and using arbitrary numbers of replications ($J$). This hinders reproducibility and efficiency. We propose the Test-Informed Simulation Count Algorithm (TISCA) to address these shortcomings. TISCA integrates Welch's t-tests with power analysis, iteratively running simulations until a pre-specified power (e.g., 0.8) is achieved for detecting a user-defined minimum detectable effect size (MDE) at a given significance level ($alpha$). This yields a statistically justified simulation count ($J$) and rigorous model comparisons. Our bibliometric study confirms the heterogeneity of current practices regarding $J$. A case study revisiting McJames et al. (2024) demonstrates TISCA identifies sufficient simulations ($J=500$ vs. original $J=1000$), saving computational resources while providing statistically sound evidence. TISCA promotes rigorous, efficient, and sustainable simulation practices in causal inference and beyond.