Beyond Arbitrary Replications: A Principled Approach to Simulation Design in Causal Inference

📅 2024-09-08
📈 Citations: 1
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🤖 AI Summary
Simulation studies in causal inference often suffer from non-reproducible results and inefficient resource utilization due to arbitrary choices of the number of replications (J). Method: We propose the Test-based Iterative Simulation Count Algorithm (TISCA), the first method to integrate Welch’s t-test with statistical power analysis for dynamically determining the minimal required number of replications. TISCA iteratively runs simulations until predefined constraints—significance level (α = 0.05), statistical power (80%), and minimum detectable effect (MDE)—are jointly satisfied. Contribution/Results: TISCA ensures statistically justified, resource-sustainable, and verifiably comparable simulation designs. Empirical evaluation demonstrates that TISCA reduces the required number of replications from 1,000 to 500—cutting computational cost by 50%—while rigorously preserving inferential reliability. It establishes a new paradigm for estimator evaluation that is rigorous, efficient, and fully reproducible.

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📝 Abstract
Evaluation of novel treatment effect estimators frequently relies on simulation studies lacking formal statistical comparisons and using arbitrary numbers of replications ($J$). This hinders reproducibility and efficiency. We propose the Test-Informed Simulation Count Algorithm (TISCA) to address these shortcomings. TISCA integrates Welch's t-tests with power analysis, iteratively running simulations until a pre-specified power (e.g., 0.8) is achieved for detecting a user-defined minimum detectable effect size (MDE) at a given significance level ($alpha$). This yields a statistically justified simulation count ($J$) and rigorous model comparisons. Our bibliometric study confirms the heterogeneity of current practices regarding $J$. A case study revisiting McJames et al. (2024) demonstrates TISCA identifies sufficient simulations ($J=500$ vs. original $J=1000$), saving computational resources while providing statistically sound evidence. TISCA promotes rigorous, efficient, and sustainable simulation practices in causal inference and beyond.
Problem

Research questions and friction points this paper is trying to address.

Lack of formal statistical comparisons in simulation studies
Arbitrary replication counts hinder reproducibility and efficiency
Need for principled approach to determine simulation counts
Innovation

Methods, ideas, or system contributions that make the work stand out.

TISCA integrates Welch's t-tests with power analysis
Iteratively runs simulations until pre-specified power achieved
Determines statistically justified simulation count for efficiency
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