🤖 AI Summary
研究使用DINOv2模型结合轻量级适应机制ECA和特定损失函数，对1546张眼睑结膜图像进行二分类，以实现自动分级，减少沙眼流行率调查的成本和变异性。
📝 Abstract
Automated grading of conjunctival photographs could reduce the cost and variability of trachoma prevalence surveys, but the relative value of modern pretrained visual representations, lightweight feature adaptation, and training-objective design has not been established under a common protocol. This study presents a controlled evaluation for binary classification of Trachomatous Inflammation-Follicular (TF) versus Normal using 1,546 images from the public UCSF/Lietman collection. Images are processed using the OPTED pipeline for zero-shot tarsal-conjunctiva segmentation, alignment, cropping, and standardization. We first compare six pretrained backbones using a common classification pipeline and then evaluate four lightweight adaptation mechanisms on DINOv2 ViT-B/14. Under stratified five-fold cross-validation, DINOv2 with Efficient Channel Attention (ECA) and focal-plus-center loss achieved 91.66 +/- 0.97% accuracy, 90.69 +/- 1.10% macro-F1, and 96.06 +/- 0.71% AUC. ECA introduces only five learnable parameters while matching the performance of substantially larger alternatives. Objective ablation further showed that ECA did not consistently improve plain DINOv2 across loss functions; the lowest-variance 91.66% accuracy was obtained with cross-entropy plus center loss. Overall, the fine-tuned DINOv2 representation provided most of the predictive performance, while ECA offered a highly parameter-efficient refinement whose effect depended on the training objective. The resulting workflow provides a reproducible benchmark for active trachoma image classification.