Task- and Metric-Specific Signal Quality Indices for Medical Time Series

📅 2026-02-12
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📝 Abstract
Medical time series such as electrocardiograms (ECGs) and photoplethysmograms (PPGs) are frequently affected by measurement artifacts due to challenging acquisition environments, such as in ambulances and during routine daily activities. Since automated algorithms for analyzing such signals increasingly inform clinically relevant decisions, identifying signal segments on which these algorithms may produce unreliable outputs is of critical importance. Signal quality indices (SQIs) are commonly used for this purpose. However, most existing SQIs are task agnostic and do not account for the specific algorithm and performance metric used downstream. In this work, we formalize signal quality as a task- and metric-dependent concept and propose a perturbation-based SQI (pSQI) that aims to detect an algorithm's performance degradation on an input signal with respect to a metric. The pSQI is defined as the worst-case value of the performance metric under an additive, colored Gaussian noise perturbation with a lower-bounded signal-to-noise ratio. We introduce formal requirements for task- and metric-specific SQIs, including monotonicity of the metric in expectation and maximal separation under thresholding. Experiments on R-peak detection and atrial fibrillation classification benchmarks demonstrate that the proposed pSQI consistently outperforms existing feature- and deep learning-based SQIs in identifying unreliable inputs without requiring training.
Problem

Research questions and friction points this paper is trying to address.

signal quality index
medical time series
task-specific
metric-dependent
algorithm reliability
Innovation

Methods, ideas, or system contributions that make the work stand out.

task-specific signal quality
metric-dependent SQI
perturbation-based SQI
colored Gaussian noise
performance degradation detection
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J
Jad Haidamous
KIS*MED - AI Systems in Medicine, Technical University of Darmstadt, Darmstadt, Germany
Christoph Hoog Antink
Christoph Hoog Antink
Professor, TU Darmstadt
AI in MedicineMultisensor Data FusionMedical Signal ProcessingMachine LearningUnobtrusive