GAD-MambaUNet: Direction-Group Mamba with Gradient-Adaptive DINOv3 Distillation for Lightweight Medical Image Segmentation

📅 2026-09-22
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🤖 AI Summary
本文提出GAD-MambaUNet,通过结合局部建模、方向组状态空间交互和基于DINOv3的梯度自适应蒸馏方法,解决轻量级医学图像分割中的上下文建模问题。
📝 Abstract
In this paper, we proposed GAD-MambaUNet, a lightweight medical image segmentation network that combines efficient local modeling, direction--group state-space interaction, and training-time foundation-model supervision. To improve contextual modeling in compact segmentation networks, we introduced Direction-Group Graph Selective Scan (DG-GSS), which treated scan-direction and channel-group responses as graph nodes and enabled structured information exchange before multi-directional fusion. We further incorporated DINOv3-GAD supervision, where a frozen DINOv3 teacher provided semantic guidance during training, and Gradient-Adaptive Distillation dynamically regulated the distillation strength. GAD-MambaUNet achieves a favorable accuracy--efficiency balance compared with representative lightweight and general segmentation methods. Ablation studies further verify the effectiveness of DG-GSS and training-time DINOv3-GAD supervision. In future work, we will explore more flexible teacher--student alignment strategies and extend the proposed framework to more diverse medical segmentation scenarios, such as multi-class and multi-modal segmentation tasks.
Problem

Research questions and friction points this paper is trying to address.

Medical Image Segmentation
Lightweight Network
Contextual Modeling
Innovation

Methods, ideas, or system contributions that make the work stand out.

GAD-MambaUNet
Direction-Group Graph Selective Scan
Gradient-Adaptive Distillation
DINOv3-GAD supervision
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Fang Wang
Postdoc, Stanford University
Reading acquisitiondyslexiacross-linguistic researchbilingualismcognitive neuroscience
Huitao Li
Huitao Li
Duke-Nus Medical School
Medical Informatics
W
Wenhan Chao
School of Computer Science and Engineering, Beihang University, Beijing, 100191, 100083, People’s Republic of China
Z
Zheng Zhuo
College of Artificial Intelligence, Beijing Institute of Petrochemical Technology, Beijing, 102617, People’s Republic of China
X
Xinxin Yang
College of Artificial Intelligence, Beijing Institute of Petrochemical Technology, Beijing, 102617, People’s Republic of China