Panda: Unsupervised Pelvic Anomaly Detection for Real-Time MR Imaging

📅 2026-07-27
📈 Citations: 0
Influential: 0
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🤖 AI Summary
This work addresses the challenge of real-time anomaly detection in female pelvic MRI, where physiological motion, tissue deformation, and instrument-related artifacts complicate reliable identification. To circumvent the need for annotated data, the authors propose an unsupervised anomaly detection method built upon the Dinomaly framework. By freezing a pretrained DINOv2 Vision Transformer (ViT) encoder and coupling it with a noisy MLP bottleneck and a linear-attention decoder, this approach uniquely integrates a frozen ViT with a lightweight decoding architecture—effectively mitigating identity mapping while balancing accuracy and computational efficiency. Token-level cosine distances yield interpretable spatial anomaly maps, achieving 88.06% pixel-level AUROC and 95.45% frame-level specificity on a uterine fibroid subset, with an inference speed of 40.5 slices per second, thereby meeting clinical requirements for real-time deployment.
📝 Abstract
Female pelvic diseases remain an under researched area characterized by often delayed diagnosis. While pelvic MRI offers superior soft-tissue contrast for diagnosis and image-guided procedures, real-time anomaly detection remains challenging due to physiological motion, tissue deformation, and instrument artifacts. Existing supervised approaches are impractical, as adverse events are rare, heterogeneous, and difficult to annotate. We present a Dinomaly-based unsupervised anomaly detection framework adapted for pelvic MRI that learns normative representations from healthy cases and flags deviations without requiring labels. Our approach leverages a frozen DINOv3 Vision Transformer encoder combined with a noisy MLP bottleneck and Linear Attention decoder to prevent identity mapping while maintaining computational efficiency. Anomalies are localized via per-token cosine distance between encoder and decoder representations, yielding spatial anomaly maps that provide immediate feedback at the scanner to support radiologist decision-making and adaptive protocol adjustment. Evaluated on a curated subset of the Uterine Myoma Dataset, the framework achieves a pixel-level AUROC of 88.06% and high specificity (95.45%) at frame level at 40.5 slices/s, meeting real-time clinical deployment requirements. The spatial anomaly maps and frame-level scores provide immediate, localized feedback at the scanner to support radiologist decision-making and adaptive protocol adjustment during active procedures.
Problem

Research questions and friction points this paper is trying to address.

pelvic MRI
anomaly detection
real-time imaging
unsupervised learning
medical imaging
Innovation

Methods, ideas, or system contributions that make the work stand out.

unsupervised anomaly detection
real-time MRI
Vision Transformer
spatial anomaly mapping
DINOv3
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Anika Knupfer
Institute of Information Processing, Leibniz University Hannover, Hannover, Germany; CAIMED, L3S, Hannover, Germany
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Maximilian Lindholz
Department of Radiology, Charité Universitätsmedizin Berlin, Berlin, Germany
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Johanna Paula Müller
Image Data Exploration and Analysis Lab, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany
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Jordina Aviles Verdera
Institute of Information Processing, Leibniz University Hannover, Hannover, Germany; CAIMED, L3S, Hannover, Germany
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Smiti Tripathy
Institute for Radiology, University Hospital Erlangen, Erlangen, Germany
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Susanne Schulz-Heise
Institute for Radiology, University Hospital Erlangen, Erlangen, Germany
Jana Hutter
Jana Hutter
UKER/FAU Erlangen // King's College London
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