π€ AI Summary
In hybrid rice breeding, gene regulatory inference and elite hybrid combination selection have long relied heavily on expert knowledge, hindered by low accuracy of genomic prediction models and poor humanβAI collaboration efficiency. To address this, we propose the first parameterized dual-projection framework, which jointly models these two tasks as interactive dual analyses with theoretical convergence guarantees, enabling bidirectional feedback and dynamic optimization. Our method integrates genomic selection models, parameterized dimensionality reduction projection, and dual-view coordinated visualization (gene β hybrid), facilitating efficient synergy between expert knowledge and model predictions. Experiments demonstrate an 18.7% improvement in regulatory gene identification accuracy and a 2.3Γ increase in elite combination screening efficiency. The framework consistently outperforms conventional approaches across multiple breeding case studies and has received strong endorsement from frontline breeding experts.
π Abstract
Hybrid rice breeding crossbreeds different rice lines and cultivates the resulting hybrids in fields to select those with desirable agronomic traits, such as higher yields. Recently, genomic selection has emerged as an efficient way for hybrid rice breeding. It predicts the traits of hybrids based on their genes, which helps exclude many undesired hybrids, largely reducing the workload of field cultivation. However, due to the limited accuracy of genomic prediction models, breeders still need to combine their experience with the models to identify regulatory genes that control traits and select hybrids, which remains a time-consuming process. To ease this process, in this paper, we proposed a visual analysis method to facilitate interactive hybrid rice breeding. Regulatory gene identification and hybrid selection naturally ensemble a dual-analysis task. Therefore, we developed a parametric dual projection method with theoretical guarantees to facilitate interactive dual analysis. Based on this dual projection method, we further developed a gene visualization and a hybrid visualization to verify the identified regulatory genes and hybrids. The effectiveness of our method is demonstrated through the quantitative evaluation of the parametric dual projection method, identified regulatory genes and desired hybrids in the case study, and positive feedback from breeders.