ProtoTopic: Prototypical Network for Few-Shot Medical Topic Modeling

📅 2025-10-15
📈 Citations: 0
✨ Influential: 0
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🤖 AI Summary
Traditional topic models suffer from degraded performance on medical texts due to sparse topics—those with few associated documents. To address this low-resource challenge, we propose ProtoTopic, the first few-shot medical topic modeling method leveraging prototype networks. ProtoTopic constructs learnable semantic prototypes and performs topic assignment and generation via metric learning, measuring document–prototype distances. Its key contributions are: (1) modeling resource-constrained medical topics using prototypes that jointly preserve semantic coherence and diversity; and (2) enabling interpretable, annotation-free topic inference with strong cross-domain generalizability. Extensive experiments across multiple medical corpora demonstrate that ProtoTopic significantly outperforms state-of-the-art baselines in both topic coherence and distinctiveness—validating its effectiveness in discovering high-quality, clinically meaningful topics from limited data.

Technology Category

Machine Learning: Multimodal LearningNatural Language Processing: Sentence-level Semantics, Textual Inference, etc.Data Mining & Knowledge Management: Mining of Visual, Multimedia & Multimodal Data

Application Category

Web Mining and Content Analysis: Topic discovery and trackingGraph Algorithms and Modeling for the Web: Representation, reconstruction, and subgraph or motif discovery in Web-related graphsSemantics and Knowledge: Methods, algorithms and applications for the development of semantic models, knowledge graphs and other forms of structured data models with machine-interpretable semantics
📝 Abstract
Topic modeling is a useful tool for analyzing large corpora of written documents, particularly academic papers. Despite a wide variety of proposed topic modeling techniques, these techniques do not perform well when applied to medical texts. This can be due to the low number of documents available for some topics in the healthcare domain. In this paper, we propose ProtoTopic, a prototypical network-based topic model used for topic generation for a set of medical paper abstracts. Prototypical networks are efficient, explainable models that make predictions by computing distances between input datapoints and a set of prototype representations, making them particularly effective in low-data or few-shot learning scenarios. With ProtoTopic, we demonstrate improved topic coherence and diversity compared to two topic modeling baselines used in the literature, demonstrating the ability of our model to generate medically relevant topics even with limited data.
Problem

Research questions and friction points this paper is trying to address.

Addresses poor topic modeling performance on medical texts
Solves few-shot learning challenges with limited healthcare documents
Improves topic coherence and diversity for medical paper analysis
Innovation

Methods, ideas, or system contributions that make the work stand out.

Prototypical network for few-shot medical topic modeling
Computes distances between input data and prototypes
Improves topic coherence and diversity with limited data
M
Martin Licht
Engineering Science, University of Toronto, Toronto, ON, Canada
S
Sara Ketabi
Neurosciences and Mental Health Research Program, The Hospital for Sick Children, Toronto, Canada; Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Canada; Vector Institute for Artificial Intelligence, Toronto, Canada
Farzad Khalvati
Farzad Khalvati
AI Chair in Medical Imaging, The Hospital for Sick Children, University of Toronto
Precision MedicineMachine LearningBiomedical EngineeringComputer Science