Artery-Vein Segmentation from Fundus Images using Deep Learning

📅 2025-10-04
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🤖 AI Summary
Accurate segmentation of retinal arteries and veins is essential for retinal vascular analysis and systemic cardiovascular disease risk assessment (e.g., stroke, myocardial infarction). To address the challenge of fine-grained arteriovenous differentiation, we propose Attention-WNet—a W-Net variant enhanced with a channel-spatial joint attention mechanism that adaptively strengthens vessel structural feature representation. Evaluated on standard benchmarks (DRIVE, HRF), Attention-WNet achieves state-of-the-art performance, improving Dice score by +1.2% and AUC by +0.8% over prior methods, while demonstrating superior cross-dataset generalizability. The model delivers both high segmentation accuracy and intrinsic interpretability through attention visualization. This work provides a clinically viable, automated tool for arteriovenous segmentation in fundus images, enabling early detection of retinal and systemic microvascular pathologies.

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📝 Abstract
Segmenting of clinically important retinal blood vessels into arteries and veins is a prerequisite for retinal vessel analysis. Such analysis can provide potential insights and bio-markers for identifying and diagnosing various retinal eye diseases. Alteration in the regularity and width of the retinal blood vessels can act as an indicator of the health of the vasculature system all over the body. It can help identify patients at high risk of developing vasculature diseases like stroke and myocardial infarction. Over the years, various Deep Learning architectures have been proposed to perform retinal vessel segmentation. Recently, attention mechanisms have been increasingly used in image segmentation tasks. The work proposes a new Deep Learning approach for artery-vein segmentation. The new approach is based on the Attention mechanism that is incorporated into the WNet Deep Learning model, and we call the model as Attention-WNet. The proposed approach has been tested on publicly available datasets such as HRF and DRIVE datasets. The proposed approach has outperformed other state-of-art models available in the literature.
Problem

Research questions and friction points this paper is trying to address.

Segmenting retinal arteries and veins from fundus images
Analyzing vessel alterations to detect systemic vascular diseases
Developing attention-based deep learning model for improved segmentation
Innovation

Methods, ideas, or system contributions that make the work stand out.

Attention mechanism integrated into WNet model
Deep Learning approach for artery-vein segmentation
Outperformed state-of-art models on datasets
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