Disentangle-then-Align: Non-Iterative Hybrid Multimodal Image Registration via Cross-Scale Feature Disentanglement

📅 2026-03-20
📈 Citations: 0
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🤖 AI Summary
This work addresses the challenges in multimodal image registration, where modality-specific information often leaks into the shared feature space and existing methods struggle to jointly model global rigid alignment and local non-rigid deformations. To overcome these limitations, the authors propose HRNet, which employs a shared backbone enhanced with modality-specific batch normalization (MSBN) and introduces a cross-scale decoupling and adaptive projection module (CDAP) to effectively suppress modality interference. Furthermore, a hybrid parameter prediction module (HPPM) is designed to unify the prediction of rigid transformations and non-rigid deformation fields within an end-to-end, non-iterative framework. The proposed method achieves state-of-the-art performance in both rigid and non-rigid registration across four multimodal datasets.

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📝 Abstract
Multimodal image registration is a fundamental task and a prerequisite for downstream cross-modal analysis. Despite recent progress in shared feature extraction and multi-scale architectures, two key limitations remain. First, some methods use disentanglement to learn shared features but mainly regularize the shared part, allowing modality-private cues to leak into the shared space. Second, most multi-scale frameworks support only a single transformation type, limiting their applicability when global misalignment and local deformation coexist. To address these issues, we formulate hybrid multimodal registration as jointly learning a stable shared feature space and a unified hybrid transformation. Based on this view, we propose HRNet, a Hybrid Registration Network that couples representation disentanglement with hybrid parameter prediction. A shared backbone with Modality-Specific Batch Normalization (MSBN) extracts multi-scale features, while a Cross-scale Disentanglement and Adaptive Projection (CDAP) module suppresses modality-private cues and projects shared features into a stable subspace for matching. Built on this shared space, a Hybrid Parameter Prediction Module (HPPM) performs non-iterative coarse-to-fine estimation of global rigid parameters and deformation fields, which are fused into a coherent deformation field. Extensive experiments on four multimodal datasets demonstrate state-of-the-art performance on rigid and non-rigid registration tasks. The code is available at the project website.
Problem

Research questions and friction points this paper is trying to address.

multimodal image registration
feature disentanglement
hybrid transformation
modality-private cues
multi-scale frameworks
Innovation

Methods, ideas, or system contributions that make the work stand out.

feature disentanglement
hybrid registration
non-iterative optimization
cross-scale representation
multimodal image registration
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