The ethics of artificial intelligence in the life sciences: Universality, cultural diversity and an architecture of care

📅 2026-08-05
📈 Citations: 0
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🤖 AI Summary
This work addresses the unique ethical challenges posed by the application of artificial intelligence in the life sciences, arguing for a governance framework that moves beyond traditional “constraint”-based paradigms. Integrating insights from neuroscience, cognitive psychology, and AI ethics, the study proposes a novel “nurturing”-oriented governance model grounded in the Global Neuronal Workspace theory and a non-maximizing affective reward mechanism. This approach emulates the human cognitive-affective cycle of “desire–affection–satisfaction,” balancing ethical universality with moral diversity. The framework introduces a low-computational-cost architecture alongside a care-centered institutional design, offering both a theoretical foundation and a set of critical open questions to guide the ethical development and societal integration of AI systems in the life sciences.
📝 Abstract
The life sciences and health research have started to benefit from artificial intelligence, which raises ethical concerns that are real but, we argue, not special. Any science should be governed by values that rest on how the human brain is built and socialised rather than anything distinct to artificial intelligence. Importantly, the human brain has a different, much less costly computational architecture than these machines. This is achieved through the orchestration of a global neuronal workspace, and through reward best described not as a quantity to be maximised but as a continuous cycle of wanting, liking and satiety. As such, this creates the deep tension running through the ethics of the human person, between the universality of ethical judgement and the diversity of morals. The brain networks of the global workspace and emotion are universally shared, but the diversity of content is shaped by epigenetic appropriation of the particulars of the physical, social and cultural world, which makes every person unique. Still, if we were to build machines on these principles rather than the present unaffordable reward maximisers, the question of their governance would change from restraint to upbringing. We set out the institutions such a future would require, together with the questions that remain open.
Problem

Research questions and friction points this paper is trying to address.

artificial intelligence
ethics
cultural diversity
life sciences
governance
Innovation

Methods, ideas, or system contributions that make the work stand out.

global neuronal workspace
reward cycle
epigenetic appropriation
architecture of care
AI ethics
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Jean-Pierre Changeux
Jean-Pierre Changeux
Emeritus professor, Pasteur Institute
neurosciencemolecular biology
G
Gustavo Deco
Center for Brain and Cognition, Computational Neuroscience Group, Faculty of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain; Institució Catalana de la Recerca i Estudis Avançats (ICREA), Barcelona, Spain; International Centre for Flourishing, Universities of Oxford (UK), Aarhus (Denmark) and Pompeu Fabra (Spain)
M
Morten L. Kringelbach
International Centre for Flourishing, Universities of Oxford (UK), Aarhus (Denmark) and Pompeu Fabra (Spain); Centre for Eudaimonia and Human Flourishing, Linacre College, University of Oxford, Oxford, UK; Department of Psychiatry, University of Oxford, Oxford, UK; Center for Music in the Brain, Department of Clinical Medicine, Aarhus University, Aarhus, DK