Attenuation artifact detection and severity classification in intracoronary OCT using mixed image representations

📅 2025-03-07
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🤖 AI Summary
In intracoronary optical coherence tomography (OCT), residual blood and air bubbles induce attenuation artifacts that obscure critical vascular structures, necessitating repeated acquisitions, prolonging procedure time, and increasing contrast agent usage. Due to their highly heterogeneous morphologies, such artifacts are challenging to detect and grade automatically. To address this, we propose the first convolutional neural network (CNN) architecture integrating dual-domain representations—Cartesian and polar coordinates—to enable A-line–level, fine-grained detection and classification into three severity levels: none, mild, and severe. Our method performs end-to-end artifact localization and severity grading, thereby supporting targeted re-scan decisions. In frame-level evaluation, it achieves F-scores of 0.77 for mild and 0.94 for severe artifacts. Full-scan inference requires only ~6 seconds, substantially improving clinical workflow efficiency.

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📝 Abstract
In intracoronary optical coherence tomography (OCT), blood residues and gas bubbles cause attenuation artifacts that can obscure critical vessel structures. The presence and severity of these artifacts may warrant re-acquisition, prolonging procedure time and increasing use of contrast agent. Accurate detection of these artifacts can guide targeted re-acquisition, reducing the amount of repeated scans needed to achieve diagnostically viable images. However, the highly heterogeneous appearance of these artifacts poses a challenge for the automated detection of the affected image regions. To enable automatic detection of the attenuation artifacts caused by blood residues and gas bubbles based on their severity, we propose a convolutional neural network that performs classification of the attenuation lines (A-lines) into three classes: no artifact, mild artifact and severe artifact. Our model extracts and merges features from OCT images in both Cartesian and polar coordinates, where each column of the image represents an A-line. Our method detects the presence of attenuation artifacts in OCT frames reaching F-scores of 0.77 and 0.94 for mild and severe artifacts, respectively. The inference time over a full OCT scan is approximately 6 seconds. Our experiments show that analysis of images represented in both Cartesian and polar coordinate systems outperforms the analysis in polar coordinates only, suggesting that these representations contain complementary features. This work lays the foundation for automated artifact assessment and image acquisition guidance in intracoronary OCT imaging.
Problem

Research questions and friction points this paper is trying to address.

Detects and classifies attenuation artifacts in intracoronary OCT images.
Reduces repeated scans by guiding targeted re-acquisition of OCT images.
Uses mixed image representations to improve artifact detection accuracy.
Innovation

Methods, ideas, or system contributions that make the work stand out.

Convolutional neural network for artifact classification
Mixed image representations in Cartesian and polar coordinates
Automated artifact detection with high F-scores
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Pierandrea Cancian
Pierandrea Cancian
Unknown affiliation
S
Simone Saitta
Quantitative Healthcare Analysis group, Biomedical Engineering and Physics, Amsterdam UMC, the Netherlands; Quantitative Healthcare Analysis group, Informatics Institute, University of Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Amsterdam UMC, the Netherlands
X
Xiaojin Gu
Quantitative Healthcare Analysis group, Biomedical Engineering and Physics, Amsterdam UMC, the Netherlands; Quantitative Healthcare Analysis group, Informatics Institute, University of Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Amsterdam UMC, the Netherlands
R
R. V. Herten
Quantitative Healthcare Analysis group, Biomedical Engineering and Physics, Amsterdam UMC, the Netherlands; Quantitative Healthcare Analysis group, Informatics Institute, University of Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Amsterdam UMC, the Netherlands
T
Thijs J Luttikholt
Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands
J
J. Thannhauser
Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands
R
R. Volleberg
Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, the Netherlands
R
Ruben G.A. van der Waerden
Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands
J
J. V. D. Zande
Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands
C
Clarisa I. S'anchez
Quantitative Healthcare Analysis group, Biomedical Engineering and Physics, Amsterdam UMC, the Netherlands; Quantitative Healthcare Analysis group, Informatics Institute, University of Amsterdam, the Netherlands
B
B. Ginneken
Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, the Netherlands
N
N. Royen
Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands
I
Ivana Ivsgum
Quantitative Healthcare Analysis group, Biomedical Engineering and Physics, Amsterdam UMC, the Netherlands; Quantitative Healthcare Analysis group, Informatics Institute, University of Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, Amsterdam UMC, the Netherlands