Stephen T Wong
Scholar

Stephen T Wong

Google Scholar ID: C2gJxXYAAAAJ
Houston Methodist Hospital and Weill Cornell Medical College
Systems MedicineCancer NeuroscienceDigital BiologyMedical ImagingCell-cell communication
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Citations & Impact
All-time
Citations
12,754
 
H-index
54
 
i10-index
225
 
Publications
20
 
Co-authors
0
 
Contact
GitHubOpen ↗
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Academic Achievements
  • Secured funding from NIH, Chao Foundation, Dunn Foundation, DOD, CPRIT, Tina’s Wish Foundation, and others
  • Key grants include NIH R01CA238727 (brain metastasis and Alzheimer’s suppression), NIH R01CA177909 (platelets in ovarian cancer), and NIH U01CA253553 (spatiotemporal modeling of bone metastasis)
  • Developed a novel PCDH7 single-domain antibody therapy for brain metastases
  • Repurposed digoxin for Group III/IV medulloblastoma, advancing to clinical trial
  • Identified prognostic genes in glioblastoma and biomarkers in high-grade serous ovarian cancer
Research Experience
  • Affiliated with the Systems Medicine and Bioengineering (SMAB) program at Houston Methodist Academic Institute
  • Integrates bioengineering with systems medicine to understand disease mechanisms, particularly in cancer, neurological, and metabolic disorders
  • Leads research projects on brain tumors, ovarian cancer, lung disease, bone cancer, and breast cancer
  • Research includes tumor-astrocyte crosstalk, single-domain antibody therapeutics, drug repositioning, exosomal communication, immunotherapy, platelet-tumor interactions, and immuno-radiotherapy crosstalk
  • Several projects have advanced to clinical trials