Ishaan Gupta
Scholar

Ishaan Gupta

Google Scholar ID: H8yFVJYAAAAJ
Assistant Professor, Indian Institute of Technology Delhi, India
Functional Genomics
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Citations & Impact
All-time
Citations
1,766
 
H-index
18
 
i10-index
32
 
Publications
20
 
Co-authors
0
 
Contact
Emailishaan@iitd.ac.inGitHubOpen ↗LinkedInOpen ↗
Publications
3 items
Benchmarking GNN Models on Molecular Regression Tasks with CKA-Based Representation Analysis
2026
Cited
0
Understanding Virality: A Rubric based Vision-Language Model Framework for Short-Form Edutainment Evaluation
2025
Cited
0
Predicting EGFR Mutation in LUAD from Histopathological Whole-Slide Images Using Pretrained Foundation Model and Transfer Learning: An Indian Cohort Study
2025
Cited
0
Resume
Academic Achievements
  • Completed reference-quality genome assemblies of three Candida auris clade strains (2024)
  • Published on PfAP2-P’s role in malaria parasite pathogenesis in Nature Microbiology (2023)
  • Published MIST technology in npj Systems Biology and Applications (2024)
  • Developed the first single-cell isoform sequencing protocol capturing full-length transcripts
  • Built one of the world’s largest RNA-seq datasets from postmortem lungs of COVID-19 patients
  • Authored multiple high-impact publications (e.g., Gupta et al. 2014; Gupta & Villanyi et al. 2016; Raj et al. 2018; Kapoor et al. 2019; Bhatia & Makhija et al. 2022)
Research Experience
  • Leads the Gupta Lab at IIT Delhi as Principal Investigator
  • Contributing to the national GenomeIndia initiative by performing de novo assembly of mitochondrial genomes to build the first Indian mitochondrial reference genome
  • Research areas include cellular heterogeneity in host-pathogen interactions, molecular mechanisms of cancer persistence and immunotherapy, and functional consequences of genetic diversity in India
  • Developed Microarray Integrated Spatial Transcriptomics (MIST) for affordable digital pathology
  • Generated the first single-cell RNA-seq dataset from India
  • Conducted large-scale RNA-seq analysis on postmortem lung tissues from COVID-19 patients
Background
  • Faculty at Department of Biochemical Engineering and Biotechnology, IIT Delhi, India
  • Principal Investigator of the Functional Genomics Lab
  • Develops and applies omics technologies with high resolution (single-cell), high precision (isoforms), and high throughput (hundreds to millions of samples)
  • Focuses on dissecting biological complexity in the contexts of evolution and disease
  • Develops AI-based genomics solutions for precision diagnostics